| 產(chǎn)品編號 | bs-2648R |
| 英文名稱 | LAIR-2 Rabbit pAb |
| 中文名稱 | 白細(xì)胞相關(guān)免疫球蛋白樣受體2抗體 |
| 別 名 | Leukocyte-associated immunoglobulin-like receptor 2; CD306; CD 306; CD-306; CD306 antigen; LAIR 2; Leukocyte associated Ig like receptor 2; Leukocyte associated immunoglobulin like receptor 2Leukocyte-associated immunoglobulin-like receptor 2; LAIR-2; LAI |
| 研究領(lǐng)域 | 免疫學(xué) 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 14 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LAIR-2/CD306: 51-152/152 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
LAIR2 is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. LAIR2 contains one Ig-like C2-type (immunoglobulin-like) domain. There are two named isoforms. Subcellular Location: Secreted. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. SWISS: Q6ISS4 Gene ID: 3904 Database links: Entrez Gene: 3904 Human Omim: 602993 Human SwissProt: Q6ISS4 Human Unigene: 43803 Human LAIR2、LAIR1都屬于細(xì)胞黏附分子中免疫球蛋白超家族（IgSF）成員，是一種免疫細(xì)胞抑制性受體，定位于T細(xì)胞、B細(xì)胞、NK細(xì)胞及樹狀突等細(xì)胞中。 |
