| 產(chǎn)品編號(hào) | bs-21102R |
| 英文名稱 | SEZ6L2 Rabbit pAb |
| 中文名稱 | 癲癇相關(guān)蛋白6樣蛋白2抗體 |
| 別 名 | FLJ90517; PSK 1; PSK; SE6L2_HUMAN; Seizure 6 like protein 2; Seizure 6-like protein 2; Seizure related 6 homolog(mouse) like 2; SEZ6L2; Type I transmembrane receptor(seizure related protein). |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 98 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SEZ6L2: 801-910/910 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] Function: Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. Subcellular Location: Cell membrane. Endoplasmic reticulum membrane. Detected on cell surface of lung-cancer. Post-translational modifications: O-glycosylated with core 1 or possibly core 8 glycans. Similarity: Belongs to the SEZ6 family. Contains 3 CUB domains. Contains 5 Sushi (CCP/SCR) domains. SWISS: Q6UXD5 Gene ID: 26470 Database links: Entrez Gene: 26470 Human SwissProt: Q6UXD5 Human SwissProt: Q6AX42 Xenopus laevis Unigene: 6314 Human |
