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Caspase-7 Recombinant Rabbit mAb (bsm-60304R)  
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產(chǎn)品編號(hào) bsm-60304R
英文名稱(chēng) Caspase-7 Recombinant Rabbit mAb
中文名稱(chēng) 半胱胺酸蛋白酶-7重組兔單抗
別    名 caspase-7 isoform alpha subunit p20; Apoptosis related cysteine peptidase; Apoptosis Related Cysteine Protease; Apoptotic Protease MCH3; CASP 7; CASP7; Caspase7; Caspase 7; CMH 1; CMH1; ICE LAP3; ICE like Apoptotic Protease 3; MCH3; CASP7_HUMAN.  
研究領(lǐng)域 心血管  信號(hào)轉(zhuǎn)導(dǎo)  骨髓細(xì)胞  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Recombinant
克 隆 號(hào) C7G8
交叉反應(yīng) Human,Mouse
產(chǎn)品應(yīng)用 WB=1:500-1000,IHC-P=1:200-1:1000,IHC-F=1:50-100,IF=1:50-100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20/33 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Caspase-7 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].

SWISS:
P55210

Gene ID:
840

產(chǎn)品圖片
Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:2000 Primary ab incubation condition: 2 hours at room temperature Lysate: HeLa, RAW264.7, Jurkat Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 34 kDa Observed MW: 18, 32, 35 kDa
Tissue: Human colon Section type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for bsm-60304R
Tissue: Human liver cancer Section type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for bsm-60304R
Tissue: Human breast cancer Section type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for bsm-60304R
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