產(chǎn)品編號 | IHC0419H |
英文名稱 | Human MAOB Ready-To-Use IHC Kit |
中文名稱 | 人單胺氧化酶B即用型免疫組化試劑盒 |
別 名 | 6330414K01Rik; Adrenalin oxidase; Amine oxidase (flavin containing); Amine oxidase [flavin-containing] B; AOFB_HUMAN; MAO; brain; MAO; platelet; MAO-B; MAOB; MGC26382; Monoamine oxidase B; Monoamine oxidase type B |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
MAOB (Monoamine Oxidase B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species. SWISS: P27338 Gene ID: 4129 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0419H (Human MAOB IHC Kit).
|