| 產(chǎn)品編號(hào) | IHC0432H |
| 英文名稱 | Human Placental alkaline phosphatase (PLAP) Ready-To-Use IHC Kit |
| 中文名稱 | 人堿性磷酸酶即用型免疫組化試劑盒 |
| 別 名 | Alkaline phosphatase; Alkaline phosphatase placental; Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; ALP; Alp1; ALPP; FLJ61142; Germ-cell alkaline phosphatase; nagao isozyme; PALP; PLAP; PLAP-1 |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized. Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA). A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. SWISS: P05187 Gene ID: 250 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human placenta tissue slide using IHC0432H (Human Placental alkaline phosphatase (PLAP) IHC Kit).
Immunohistochemical analysis of paraffin embedded human liver tissue slide using IHC0432H (Human Placental alkaline phosphatase (PLAP) IHC Kit).
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