| 產(chǎn)品編號(hào) | IHC0442M |
| 英文名稱 | Mouse PON1 Ready-To-Use IHC Kit |
| 中文名稱 | 小鼠芳香酯酶1(對(duì)氧磷酶)即用型免疫組化試劑盒 |
| 別 名 | PON1; A esterase 1; A-esterase 1; Aromatic esterase 1; Arylesterase B type; ESA; Esterase A; K 45; K-45; MVCD5; Paraoxonase 1; Paraoxonase; Paraoxonase B type; Paraoxonase1; PON 1; PON; PON-1; PON1_HUMAN; Serum aryldiakylphosphatase; Serum aryldialkylphos |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease. SWISS: P27169 Gene ID: 5444 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse liver tissue slide using IHC0442M (Mouse PON1 IHC Kit).
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