產(chǎn)品編號(hào) | IHC0444H |
英文名稱 | Human Peroxiredoxin 3 Ready-To-Use IHC Kit |
中文名稱 | 人硫氧還蛋白還原酶3即用型免疫組化試劑盒 |
別 名 | AOP-1; AOP1; HBC189; MER5; PRDX3; PRO1748; prx-III; SP-22 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol. SWISS: P30048 Gene ID: 10935 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human liver tissue slide using IHC0444H (Human Peroxiredoxin 3 IHC Kit).
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