ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量
38/45kDa
性 狀
Lyophilized or Liquid
濃 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human RNF39
亞 型
IgG
純化方法
affinity purified by Protein A
儲 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹
background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF39 (RING finger protein 39), also known as HZFW, HZF or LIRF, is a 420 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger and one SPRY domain. Expressed in testis, RNF39 is thought to play a role in maintaining prolonged LTP (long term-potentiation, or the process by which synaptic strength continues to increases following chemical stimulation). Via its ability to influence the length of the LTP response, RNF39 functions to regulate early synaptic plasticity. Multiple isoforms of RNF39 exist due to alternative splicing events.
Function: May play a role in prolonged long term-potentiation (LTP) maintenance.
