| 產(chǎn)品編號 |
bs-21046R-Bio |
| 英文名稱 |
Rabbit Anti-POU2F3/Biotin Conjugated antibody
|
| 中文名稱 |
生物素標記的轉(zhuǎn)錄因子POU2F3抗體 |
| 別 名 |
class 2;
Epoc 1;
Epoc1;
HGNC19864;
Oct 11;
Oct-11;
OCT11;
Octamer binding transcription factor 11;
Octamer-binding protein 11;
Octamer-binding transcription factor 11;
OTF-11;
PLA 1;
PLA1;
PLA1 protein;
PO2F3_HUMAN;
POU class 2 homeobox 3;
POU domain;
POU domain transcription factor OCT11a;
POU domain, class 2, transcription factor 3;
POU transcription factor;
POU2F3;
Skn 1a;
transcription factor 3;
Transcription factor PLA-1;
Transcription factor Skn-1;
Transcription factor Skn1. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領域 |
腫瘤 細胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 細胞分化 表觀遺傳學 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應 |
(predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, )
|
| 產(chǎn)品應用 |
WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
47kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human POU2F3 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Function:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen.
Subcellular Location:
Nucleus.
Tissue Specificity:
Specifically expressed in epidermis and cultured keratinocytes.
Similarity:
Belongs to the POU transcription factor family.
Class-2 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain.
Database links:
Entrez Gene: 25833 Human
Entrez Gene: 18988 Mouse
Entrez Gene: 116544 Rat
Omim: 607394 Human
SwissProt: Q9UKI9 Human
SwissProt: P31362 Mouse
SwissProt: P42571 Rat
Unigene: 227115 Human
Unigene: 325445 Mouse
Unigene: 436650 Mouse
Unigene: 81060 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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